Ursodeoxycholic acid 128-13-2 Sistemụ nri nri cholagogic
Ụgwọ:T/T, L/C
Isi mmalite ngwaahịa:China
Ọdụ ụgbọ mmiri:Beijing/Shanghai/Hangzhou
Ike mmepụta:2000kg / ọnwa
Nye iwu (MOQ):25kg
Etiti oge:3 ụbọchị ọrụ
Ọnọdụ nchekwa:Echekwara ya na ebe dị jụụ, ebe akọrọ, okpomọkụ ụlọ.
Ihe ngwugwu:drum
Nha ngwugwu:25kg/drum
Ozi nchekwa:Ọ bụghị ngwongwo dị ize ndụ
Okwu mmalite
Ursodeoxycholic acid (UDCA), makwaara dị ka ursodiol, bụ bile acid nke abụọ, nke a na-emepụta n'ime ụmụ mmadụ na ọtụtụ ụdị ndị ọzọ sitere na metabolism site na nje bacteria eriri afọ.A na-emepụta ya na imeju n'ụdị ụfọdụ, a na-amata ya na mbụ na bile bear, nke bụ aha ya Ursus.N'ụdị dị ọcha, ejirila ya gwọọ ma ọ bụ gbochie ọtụtụ ọrịa imeju ma ọ bụ bile ducts.
A na-eji UDCA dị ka ọgwụgwọ ahụike na ọrịa gallstone (cholelithiasis) na maka biliary sludge.UDCA na-enyere aka ibelata saturation cholesterol nke bile ma na-eduga na mgbaze nke gallstones nwere cholesterol nwayọọ nwayọọ.
Enwere ike inye UDCA mgbe ịwachara ahụ bariatric iji gbochie cholelithiasis, nke a na-emekarị n'ihi oke ibu ibu na-emepụta biliary cholesterol oversaturation yana biliary dyskinesia mgbanwe hormonal nke abụọ.
Nkọwapụta (EP10)
| Ihe | Nkọwapụta |
| Ọdịdị | Na-acha ọcha ma ọ bụ ọ fọrọ nke nta ka ọ bụrụ ntụ ntụ |
| Solubility | Nke a na-adịghị ahụkebe n'ime mmiri, na-agbaze kpamkpam na ethanol (96%), soluble ntakịrị na acetone, ọ fọrọ nke nta ka ọ bụrụ ihe na-adịghị ike na methylene chloride. |
| Ebe mgbaze | 202-204 ℃ |
| njirimara | Otu ụdịdị IR dị ka ursodeoxycholic acid CRS |
| Ebe bụ isi na chromatogram enwetara na ngwọta nnwale (b) yiri n'ọnọdụ, agba na nha na ntụpọ ụkpụrụ dị na chromatogram nwetara site na ntụnye ntụaka (a). | |
| Nkwusioru enwetara bụ green-acha anụnụ anụnụ. | |
| Ntụgharị anya pụrụ iche | +58.0~+62.0° |
| adịghị ọcha C | Lithocholic acid ≤ 0.1% |
| Ihe emetụtara (HPLC) | adịghị ọcha A: chenodeoxycholic acid ≤ 1.0% |
| adịghị ọcha na-akọwapụtaghị ≤ 0.1% | |
| ngụkọta ≤ 1.5% | |
| Ọla dị arọ | ICH Q3D |
| Ọnwụ na ihicha | ≤ 1.0% |
| Sulfated uyi | ≤0.1% |
| Nyocha | 99.0% ~ 101% (ihe akpọnwụwo) |
| Ihe mgbaze fọdụrụnụ | Acetone ≤ 5000 ppm Ethyl acetate ≤ 5000 ppm Isopropanol ≤ 5000 ppm Ethanol ≤ 5000 ppm |
| Nnwale Microbiological | Ngụkọta ọnụ ọgụgụ microbial aerobic ≤ 10³CFU/g Ngụkọta yist na ebu bụ ≤ 10²CFU/g Escherichia coli: Adịghị na 1 g Salmonella: Adịghị na 10 g |
| Njirimara ndị ọzọ | |
| Nkesa nha urughuru | 100% ngafe nọmba 180 sieve (100% gafere 80 mesh sieve) |
