Ngwaahịa

Alprostadil, akpọkwara Prostaglandin E1 ma ọ bụ PEG1.Ọ dị n'ime ahụ nke ihe ndị na-arụ ọrụ ndụ, dị ka otu n'ime ezinụlọ prostaglandin, ọ bụ ihe a ma ama na-arụ ọrụ physiologically endogenous.

Enwere ike iji ya ozugbo na akwara dị nro nke vaskụla, iji gbasaa arịa ọbara ma na-abawanye mmụba ọbara, nke nwere ike melite perfusion microcirculation.Ọ nwere ike igbochi nchịkọta platelet na mmepụta thromboxane A2, yana igbochi atherosclerosis, plaque lipid na nhazi mgbagwoju anya.

Ọ nwekwara mmetụta ndị a: iji gbasaa obere arịa ọbara na akwara obi, mbelata nguzogide vaskụla na mbelata ọbara mgbali.Iji chebe akpụkpọ ahụ platelet nke nwere ike igbochi thrombosis.Iji kpuchido myocardium ischemic, nke nwere ike belata oke infarct myocardial.Ọ na-ejikwa ọgwụ mgbochi obi.Ọ nwere ọrụ diuretic na nchekwa gbasara akụrụ, dabere na mgbasawanye nke arịa ọbara iji mee ka ọbara na-erugharị akụrụ.N'ụzọ dị otú a, ọ nwere ike wepụ nitrogen na-abụghị protein, na ịchịkwa sodium na mmiri itule.

A na-ejikarị ya eme ihe n'ụlọ ọgwụ.Dị ka maka nsogbu ọrịa shuga, ọrịa obi na-adịghị ala ala na nkụda mmụọ nke na-adịghị agwụ agwụ.Ọzọkwa ojiji na ọnọdụ dị ka congenital obi ọrịa gbagwojuru anya na pulmonary hypertension, cerebral infarction na-adịghị ala ala arterial occlusive ọrịa.Maka ụfọdụ ndị dị ka ntị chiri na mberede, oghere azụ azụ azụ, ịba ọcha n'anya ma ọ bụ gastritis na-adịghị ala ala, ọ nwekwara ọrụ.Enwere ike itinye ya n'ụlọ ọgwụ maka ọrịa ndị ọzọ dị ka ọnya duodenal, ụkọ akụrụ na-adịghị ala ala na pancreatitis.Ọ bụ ngwa na transplantation akụkụ.A na-eji ya eme ihe maka ọrịa ndị ọzọ dị ka nrụrụ erectile, ntinye ọrụ na ọbara ọgbụgba, isi femoral necrosis, lumbar disc herniation, postherpetic neuralgia na bronchial asthma.

Ọ ga-akpachara anya iji maka ndị ọrịa nwere ọrịa dịka nkụda obi, glaucoma, ọnya peptic ma ọ bụ oyi baa interstitial.Na mgbakasị ahụ mmetụta na vein, ga-egosi ihe mgbaàmà nke mbufụt dị ka ọbara ọbara, ọzịza, okpomọkụ na mgbu, nke nwere ike ime ka phlebitis.Ọ ga-akwụsịrịrị iji maka nchekwa mgbe ọnọdụ mere.