Posaconazole 171228-49-2 ọgwụ nje
Ụgwọ:T/T, L/C
Isi mmalite ngwaahịa:China
Ọdụ ụgbọ mmiri:Beijing/Shanghai/Hangzhou
Ike mmepụta:20kg / ọnwa
Nye iwu (MOQ):10g
Etiti oge:3 ụbọchị ọrụ
Ọnọdụ nchekwa:Echekwara ya na ebe dị jụụ, ebe akọrọ, okpomọkụ ụlọ.
Ihe ngwugwu:vial
Nha ngwugwu:10g / vial
Ozi nchekwa:Ọ bụghị ngwongwo dị ize ndụ
Okwu mmalite
Posaconazole bụ ọgwụ antifungal nke triazole.
A na-eji Posaconazole agwọ ọrịa Aspergillus na Candida.A na-ejikwa ya maka ọgwụgwọ nke oropharyngeal candidiasis (OPC), gụnyere OPC refractory to itraconzaole na/ma ọ bụ ọgwụgwọ fluconazole.
A na-ejikwa ya na-agwọ ọrịa na-efe efe site na Candida, Mucor, na Aspergillus ụdị n'ime ndị ọrịa nwere nnukwu mgbochi.
Nkọwapụta (ọkọlọtọ n'ụlọ)
| Ihe | Nkọwapụta |
| Ọdịdị | White ma ọ bụ ihe fọrọ nke nta ka ọ bụrụ ọcha, hygroscopic ntụ ntụ |
| Ihe | Nkọwapụta |
| Ọdịdị | Uzuzu crystalline ọcha ma ọ bụ na-acha ọcha |
| Ntughari pụrụ iche | -28.0°~-34.0° |
| Ụdị kristal | Ọ kwesịrị ịbụ kristal Ⅰ, nwere akụkụ 2-theta nke 14.4±0.2°,19.2±0.2°,21.7±0.2°,24.3±0.2°29.3±0.2° |
| njirimara | IR, HPLC |
| Ihe ndị emetụtara I | PO-R1 NMT 0.10% |
| PO-R2 NMT 0.10% | |
| PO-R3 NMT 0.10% | |
| PO-R4 NMT 0.10% | |
| PO-D3 & PO-D5 NMT 0.10% | |
| PO-D7 & PO-D10 NMT 0.10% | |
| Nke ọ bụla n'ime adịghị ọcha NMT 0.10% | |
| Mkpokọta adịghị ọcha NMT 0.5% | |
| Ihe ndị metụtara Ⅱ | PO-E NMT 0.10% |
| PO-D1 NMT 0.10% | |
| PO-R5 NMT 0.10% | |
| Ihe mgbaze fọdụrụnụ | Methanol NMT 3000ppm |
| Ethanol NMT 5000ppm | |
| Dichloromethane NMT 600ppm | |
| Tetrahydrofuran NMT 720ppm | |
| N, N-dimethyl formamide NMT 880ppm | |
| Triethylamine NMT 100ppm | |
| Dimethy sulfoxide NMT 5000ppm | |
| Mmiri | NMT 2.0% |
| Ihe fọdụrụ na mgbanye | NMT 0.1% |
| Ọla dị arọ | NMT 10pm |
| Oke microbial | Mkpokọta ikuku ikuku NMT 1000cfu/g Mkpokọta yist na ebu NMT 100cfu/g E.coli kwesịrị ịpụ |
| Nyocha | 98.0% -102.0% (na-esighi ike) |
| 98.0% -102.0% (na anhydrous na ihe mgbaze n'efu) |
